The Cane River is a river in the Pilbara region of Western Australia. With its headwaters rising west of the Hamersley Range, the river flows in a north-westerly direction through the Cane River Conservation Park and over the Onslow Coastal Plain, and eventually discharges into the Indian Ocean near Yardie Landing approximately 35 kilometres north-east of Onslow.
The river is considered to be dendritic with no major tributaries; numerous wells exist within the catchment area. The river has one large permanent pool, Jabaddar Pool, which is located downstream from the North West Coastal Highway.
The mouth of the river is a largely unmodified estuary that works as a function of tidal energy. The estuary covers a total area of 18 square kilometres that is mostly saltmarsh but with a small colony of mangroves.
